INDEPENDENT DIAGNOSTICS R&D ADVISORY
Immunoassay and protein diagnostics, from feasibility to transfer.
Independent technical judgement and practical R&D support when assay performance is uncertain, or before you commit further funding, transfer or development effort. ORIVISE is led by Dr Pompi Hazarika, who brings more than 20 years of assay science and diagnostics R&D leadership.
When teams get in touch
The assay worked. Now it doesn't, or the next step is expensive.
- Results drift between lots, runs or sites.
- A reagent or conjugate will not stay stable.
- A funding, transfer or partner decision is due.
TWO WAYS IN
Something isn't working
Troubleshooting & R&D leadership
For teams facing lot-to-lot variation, calibrator drift, matrix effects, weak signal or reagent instability, without the specialist time in house to resolve them. A focused review narrows the investigation. Defined R&D leadership can follow if you need senior capacity.
- Troubleshooting Review
- Reagent and bioconjugation strategy
- Fractional R&D leadership
Deciding whether to commit
Technical assessment & due diligence
For funded developers, investors and partners who need an honest view of what the evidence supports before committing money, a transfer or a partnership. You receive a written judgement and a plan for the evidence still missing.
- Feasibility & technical risk review
- Development and transfer readiness
- Investor technical due diligence
Supporting a group of ventures through an accelerator or university programme? See programme support →
Start with your situation.
Common starting points
Typical reasons teams contact ORIVISE
Recurring assay problem
Lot-to-lot variation, calibrator drift, weak signal, high background or reagent instability is taking up R&D time without a clear investigation route.
Transfer or scale-up decision
The assay works in one setting, but the team needs to know whether it is robust enough for verification, CDMO engagement or transfer.
Funding or partnership decision
A founder, investor or partner needs an independent view of what the data supports, what remains unproven and what should be tested next.
Stretched R&D capacity
The team needs senior diagnostics judgement for a defined period to prioritise experiments, interpret findings and support scientific leads.
How the work runs
Assess. Plan. Lead.
A strong result in one setting does not prove an assay will hold across lots, matrices or sites. Every engagement starts from the evidence you already have.
Review the data and the assay
Examine results, methods, reagent history and assumptions. Separate what the evidence supports from what remains uncertain.
Prioritise the next experiments
Rank the likely causes or risks and set out the experiments that will resolve them fastest, so limited resource goes where it matters.
Own agreed workstreams
Where engaged to lead, take responsibility for defined work: experiment design, interpretation of results and progress reporting. Experiments run through your team or agreed laboratory partners.
Led by Dr Pompi Hazarika
Independent judgement, grounded in assay science.
PhD, TU Dortmund, Germany · MSc, IIT Guwahati, India · Executive MBA Candidate, University of Birmingham, UK
Pompi brings senior diagnostics R&D judgement to assay problems and development decisions. Her experience spans feasibility, troubleshooting and new product development across immunoassay and protein-based diagnostic platforms. She previously led feasibility and new product development teams at The Binding Site, part of Thermo Fisher Scientific since 2023.
Through ORIVISE, she helps teams … with IVDR and ISO 13485 requirements in view.
An assay problem or a decision that cannot wait?
Tell me what is happening and what you need to decide. A short outline is enough to start.